|Medical Treatments: 5-Fluorouracil|
|Efudex (5-Fluorouracil) is recommended for the topical treatment of actinic or solar keratoses. In the 5% strength it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites. Safety and efficacy in other indications have not been established.
The diagnosis should be established prior to treatment, since this method has not been proven effective in other types of basal cell carcinomas. With isolated, easily accessible basal cell carcinomas, surgery is preferred since success with such lesions is almost 100%. The success rate with Efudex Cream and Solution is approximately 93%, based on 113 lesions in 54 patients.Twenty-five lesions treated with the solution produced 1 failure and 88 lesions treated with the cream produced 7 failures.
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